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What to Know About Regulations for Prebiotic Ingredients in Infant Formula
Apr 21, 2026

Prebiotic regulations for infant formula play an important role in shaping how functional ingredients are used and communicated in product development. These regulations reflect the functional role of prebiotics, particularly in supporting gut microbiota development during early life.

When breastfeeding is not feasible, infant formula is designed to support similar functional outcomes. Specific functional ingredients are incorporated into infant formula to support gut microbiota development.

For example, galacto-oligosaccharides (GOS) and long-chain fructo-oligosaccharides (lcFOS) are commonly used in infant formula as prebiotic ingredients. ³ These ingredients are not digested in the upper gut and instead reach the colon, where they help support the growth of beneficial bacteria in the infant gut. ²

By promoting beneficial bacteria such as bifidobacteria and lactobacilli, GOS and lcFOS help create a more balanced gut environment in infants²,⁴. This process produces short-chain fatty acids (SCFAs), which help maintain a lower intestinal pH and reduce the growth of harmful bacteria. ⁴

This translates into several functional benefits in infant formula applications.

Benefits of GOS & lcFOS in Infant Formula3

  • Improved digestion and nutrient absorption
  • Enhanced intestinal barrier function
  • Support for immune development through modulation of inflammatory responses
  • Softer stool consistency and more regular bowel movements

 

Formulation Considerations for GOS & lcFOS3

  • Excessive intake may cause gastrointestinal
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