ANSWER

Iron is a pivotal component of the innate immune response through its role in the generation of toxic oxygen and nitrogen intermediates. It is an essential component of haemoglobin as iron deficiency results in a reduction of haemoglobin circulation and a reduction in red blood cells. This indicates that an iron deficiency would impair functioning of the immune system.

Enclosed please find the studies/journals regarding iron and immune systems.

Hepcidin-and-Its-Role-in-Regulating-Systemic-Iron-Metabolism

Iron-homoeostasis-in-rheumatic-disease

Iron-Inactivates-the-RNA-Polymerase-NS5B-and-suppresses-subgenomic-replication-of-Hepatitis-C-Virus

Ironing-Out-the-Wrinkles-in-Host-Defense-Interactions-between-Iron-Homeostasis-and-Innate-Immunity

Modulation-of-hepatitis-C-virus-replication-by-iron-and-hepcidin-in-Huh7-hepatocytes

The-Battle-for-Iron-between-Bacterial-Pathogens-and-their-Vertebrate-Hosts

The-role-of-iron-in-the-immune-response-to-bacterial-infection