ANSWER
Low Calorie Sweetener that use below the acceptable daily intake level established by the US FDA is considered safe during pregnancy (Sylvetsky et al., 2019)
Sugar Alcohol / Nutritive Sweetener (Isomalt) |
Description |
Sources |
Polyols (Isomalt, Lactitol, Maltitol, Mannitol, Sorbitol, Xylitol And Erythritol) |
Limited evidence exists on the effects of polyols during pregnancy but safe when consumed in moderation and not suggest an increased risk in toxicity, adverse pregnancy outcomes, or neonatal issues |
Pope et al., 2014 |
Sugar alcohols (Sorbitol, Xylitol, Isomalt, Mannitol) |
Don’t contribute to excess weight gain during pregnancy, but contain calories that can be converted into fat and safe for pregnant women when use in moderation |
American Pregnancy Association, 2020 |
Synbiotic food (0.04g Inulin (HPX) as prebiotic with 0.38g Isomalt, 0.36g Sorbitol, and 0.05g Stevia) |
Consumption of synbiotic food among pregnant women has resulted in increased levels of serum calcium |
Taghizadeh et al., 2015 |
Synbiotic food (heat resistant L.sporogenes, 0.04g Inulin (HPX) as prebiotic with 0.38g Isomalt, 0.36g Sorbitol and 0.05g Stevia |
Reduces levels of Triacylglycerols (main constituents of body fat in humans ) and VLDL (Very-low-density lipoprotein) , in plasma from pregnant women |
Taghizadeh et al., 2014 |
Lozenges (consist of isomalt filler) |
The consumption of L.reuteri lozenges may be a useful adjunct in the control of pregnancy gingivitis |
Schlagenhauf et al., 2016 |
Nutritive And Non-Nutritive Sweeteners (NNS) |
Approved by the Food and Drug Administration sweeten with minimal or no carbohydrate or energy and are generally recognized as safe for lactation woman. |
Kolasa et al., 2015 |
Conclusion
Isomalt Studies (Makinen, 2016)
-
<50g/day – Adult
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<25g/day – Children
There is no guideline Acceptable Daily Intake set by the FDA, but as with all sugar alcohols they recommend moderation. It is approved for use in most countries as well in Food additives permitted in the EU (European Union) as E953.
References
Commission Regulation (EU) No 1129/2011 of 11 November 2011 amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the Council by establishing a Union list of food additives.
Kolasa, K. M., Firnhaber, G., & Haven, K. (2015). Diet for a healthy lactating woman. Clinical Obstetrics and Gynecology, 58(4), 893–901. https://doi.org/10.1097/grf.0000000000000144
Makinen, K. K. (2016). Gastrointestinal disturbances associated with the consumption of sugar alcohols with special consideration of xylitol: Scientific review and instructions for dentists and other health-care professionals. International Journal of Dentistry, 2016, 116. https://doi.org/10.1155/2016/5967907
Pope, E., Koren, G., & Bozzo, P. (2014). Sugar substitutes during pregnancy. Canadian family physician Medecin de famille canadien, 60(11), 1003–1005.
Schlagenhauf, U., Jakob, L., Eigenthaler, M., Segerer, S., Jockel-Schneider, Y., & Rehn, M. (2016). Regular consumption of Lactobacillus reuteri-containing lozenges reduces pregnancy gingivitis: an RCT. Journal of Clinical Periodontology, 43(11), 948–954. https://doi.org/10.1111/jcpe.12606
Sylvetsky, A. C., Figueroa, J., Rother, K. I., Goran, M. I., & Welsh, J. A. (2019). trends in low-calorie sweetener consumption among pregnant women in the United States. Current Developments In Nutrition, 3(4), nzz004. https://doi.org/10.1093/cdn/nzz004
Taghizadeh, M., Alizadeh, S., Asemi, Z. (2015). Effect of daily consumption of a synbiotic food on pregnancy outcomes: A double-blind randomized controlled clinical trial. Women’s Health Bulletin, 3(1), 1-6. https://doi.org/10.17795/whb-27195
Taghizadeh, M., Hashemi, T., Shakeri, H. et al. Synbiotic food consumption reduces levels of Triacylglycerols and VLDL, but not Cholesterol, LDL, or HDL in plasma from pregnant women. Lipids, 49, 155–161 (2014). https://doi.org/10.1007/s11745-013-3867-2
